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Italian Penicillin Soup Recipe

5 Stars 4 Stars 3 Stars 2 Stars 1 Star 4.1 from 21 reviews
  • Author: Mary
  • Prep Time: 10 minutes
  • Cook Time: 25 minutes
  • Total Time: 35 minutes
  • Yield: 4 servings
  • Category: Soup
  • Method: Stovetop
  • Cuisine: Italian-American

Description

Italian Penicillin Soup is a comforting and flavorful chicken soup infused with garlic, vegetables, and fresh herbs, making it a perfect remedy for colds and a wholesome meal. This hearty Italian-American classic features tender chicken, pasta, and nutritious greens simmered in a savory broth, finished with a splash of lemon juice and parsley for brightness.


Ingredients

Scale

Soup Base

  • 1 tablespoon olive oil
  • 1 small yellow onion, diced
  • 2 cloves garlic, minced
  • 2 medium carrots, sliced
  • 2 celery stalks, sliced
  • 1 teaspoon dried oregano
  • 1/2 teaspoon red pepper flakes (optional)
  • 1/2 teaspoon salt
  • 1/4 teaspoon black pepper

Broth and Main Ingredients

  • 6 cups low-sodium chicken broth
  • 2 cups shredded cooked chicken (preferably rotisserie)
  • 1 (14.5-ounce) can diced tomatoes with juice
  • 1/2 cup small pasta such as ditalini or orzo

Greens and Garnish

  • 2 cups chopped fresh spinach
  • 1 tablespoon fresh lemon juice
  • 2 tablespoons chopped fresh parsley
  • Grated Parmesan cheese for serving (optional)


Instructions

  1. Heat the olive oil and sauté aromatics: Heat olive oil in a large pot over medium heat. Add diced onion and cook until softened and translucent, about 4–5 minutes.
  2. Add garlic, carrots, and celery: Stir in minced garlic, sliced carrots, and celery. Cook together for another 5 minutes, allowing the vegetables to soften and flavors to meld.
  3. Season the vegetables: Add dried oregano, red pepper flakes if using, salt, and black pepper. Stir well to coat the vegetables evenly with the seasonings.
  4. Add broth and bring to boil: Pour in the low-sodium chicken broth and bring the mixture to a rolling boil over high heat.
  5. Incorporate tomatoes and pasta: Stir in the diced tomatoes with their juice and the small pasta choice (ditalini or orzo). Reduce heat to a simmer and cook until the pasta is al dente, approximately 8–10 minutes.
  6. Add cooked chicken and spinach: Stir in the shredded cooked chicken and chopped fresh spinach. Continue cooking for another 3–4 minutes until the spinach wilts and the soup is thoroughly heated.
  7. Finish with lemon juice and parsley: Remove soup from heat and stir in fresh lemon juice and chopped parsley just before serving. Optionally, top with grated Parmesan cheese if desired.

Notes

  • Use leftover roasted chicken or turkey as a convenient protein option.
  • For a vegetarian version, substitute chickpeas for the chicken and use vegetable broth.
  • Orzo, ditalini, or broken spaghetti noodles all work well as pasta in this soup.
  • Omit Parmesan cheese to keep the dish dairy-free.